Professor Nikita Gamper
Tutor information is taken from the Module Catalogue
Principles of Neural Science
4th Edition Kandel et al.
Kandel is great book for Neuroscience and you can access an online version of Kandel et al. Principles of Neural Science 4th edition through the University of Leeds library website.
, Bear et al 3rd edition
Chapters 24 and 25
Neuroscience, Purves et al 4th edition
Chapters 8 and 31
The second edition of Neuroscience by Purves can be accessed online for free here
To use this you will need to enter a search term eg synaptic plasticity in the box at the top.
The following links provide a simple introducton to some ot the concepts relevant to this module (and many other modules you will take).
A very good book for background is:
Introduction to genetics : a molecular approach . by Terry Brown 2012, Published by Garland Science. ISBN 978-0-8153-6509-9
How is the information encoded by genes converted to proteins?
How does PCR work?
How can we study the expression of all genes at once?
How do we make a knockout mouse?
Help with molecular biology techniques
Some textbooks that contain material that will help you with the molecular, genetic and cloning aspects of this module are below. You will find some of chapters in each book useful:
Author Revest, Patricia. P. Revest and A. Longstaff. Published Oxford : BIOS Scientific, 1998.
Author Carter, David. Title / David Carter and David Murphy. Published Harlow : Longman, 1999.
Molecular biology of the neuron
Author Davies, R. Wayne. Title / R. Wayne Davies, Brian J. Morris. Published Oxford : BIOS Scientific, 1997.
Below are links to some relevant sections from Molecular Biology of the Cell 4th edition which is freely available online. These should help you understand the concepts and fill in extra detail from the lectures. We don’t expect you to know everything that is covered by these chapters but you may find some of the extra material interesting. Refer to the learning objectives of the lectures and the module which describes what we expect you to know.
If you would rather look at a proper book, hard copies of the fifth edition can be found in the library:
Molecular biology of the cell Bruce Alberts ... [et al.] ; Published New York : Garland Science, c2008.Edition 5th ed.
From DNA to protein
This is a link to the freely available online version of Molecular Biology of the Cell 4th Edition by Alberts et al. The information in this chapter covers all the basics of transcription, splicing and translation. It provides an excellent resource for explaining the mechanisms though this is a general description and does not use examples specific to the nervous system. I would encourage you to at least read some of the sections.
This is a link to the freely available online version of Molecular Biology of the Cell 4th Edition by Alberts et al. The information in this chapter is more than you will need but provides an excellent resource for explaining the mechanisms. I would encourage you to at least read some of the sections.
Some relavant chapters that discuss the molecular underpinnings of syanptic plasticity can be found here:
The neurobiology of learning and memory / Jerry W. Rudy
Chapters 8 and 9
Mechanisms of memory / J. David Sweatt.
look at chapter 8. We should have electronic access to this book soon.
Mechanisms of memory 2nd edition (2010) / J. David Sweatt.
This is currently on order. Look at the chapter "Signalling Mechanisms"
This list was last updated on 11/03/2014