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Module Reading List

Food and Cancer, 2019/20, Semester 1
Dr James Thorne
Tutor information is taken from the Module Catalogue

Week 1 and 2 Reading

Gibney, M.J. and Nutrition Society (Great Britain), Introduction to human nutrition. 2nd ed. The human nutrition textbook series. 2009, Chichester: Wiley-Blackwell. Chapters 6, 8, 13 and 15 Core 

Alberts, B.,  Molecular biology of the cell. Sixth edition. ed. 2015, New York, NY: Garland Science, Taylor and Francis Group. 1 volume (various pagings). Chapter 6 How Cells Read the Genome: From DNA to Protein Core  Available as an Online Course Reading in Minerva 

Hanahan, D. and R.A. Weinberg, The hallmarks of cancer. Cell., 2000. 100(1): p. 57-70. Core 

Hanahan, D. and R.A. Weinberg, Hallmarks of cancer: the next generation. Cell., 2011. 144(5): p. 646-74. Core 

Weinberg, R.A., The biology of cancer. Second edition. ed. 2014, New York: Garland Science, Taylor & Francis Group. xx, 876, A 6, G 30, I 28 pages. 


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Week 3-5 Reading (NB: I do not expect you to read all of this but look through for interesting examples)

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18th November

Nutraceuticals and chemoprevention: What has oncology learnt from nutrition? Prof Mark Hull

  • Eicosapentaenoic acid and aspirin, alone and in combination, for the prevention of colorectal adenomas (seAFOod Polyp Prevention trial): a multicentre, randomised, double-blind, placebo-controlled, 2x2 factorial trial. Hull MA, et al. Lancet 2018;392:2583-2594  
  • A randomised trial of the effect of omega-3 polyunsaturated fatty acid supplements on the human intestinal microbiota. Watson et al, Gut 2018;67:1974-1983.  
  • Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice. Cai, H., et al., Sci Transl Med, 2015. 7(298): p. 298ra117.

 19th November

How does diet cause cancer? Aflatoxin and Liver cancer. Prof Yunyun Gong

  • Aflatoxin: a 50-year odyssey of mechanistic and translational toxicology. Kensler, T.W., et al., Toxicol Sci, 2011. 120 Suppl 1: p. S28-48.  
  • Protective interventions to prevent aflatoxin-induced carcinogenesis in developing countries. Groopman, J.D. et al. Annu Rev Public Health, 2008. 29: p. 187-203.  

25th November

The UK Women’s Cohort Study and Cancer. Prof Janet Cade

  • Meat consumption and risk of breast cancer in the UK Women's Cohort Study. Taylor, E.F., et al., British journal of cancer, 2007. 96(7): p. 1139-46.
  • Common dietary patterns and risk of cancers of the colon and rectum: Analysis from the United Kingdom Women's Cohort Study (UKWCS). Rada-Fernandez de Jauregui D, et al, 2018. Int J Cancer. 143(4):773-81.  
  • Cohort Profile: The UK Women’s Cohort Study (UKWCS). 2017 Cade, J. E., et al. International Journal of Epidemiology. Advanced publication. doi:10.1093/ije/dyv173 46 (2) e11.  

 26th November

Can diet prevent cancer? Brassicas. Prof Mike Morgan

 2nd December

Cholesterol, Obesity and Breast Cancer. Dr James Thorne

  • Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5.24 million UK adults. Bhaskaran K et. al., Lancet 2014; 384: 755–65.  
  • Molecular mechanisms of cancer development in obesity. Khandekar MJ et .al., nature reviews cancer 2011, 11:886-895.
  • Association of Body Mass Index and Age With Subsequent Breast Cancer Risk in Premenopausal Women. 2018. Premenopausal Breast Cancer Collaborative G, Schoemaker MJ et. Al., JAMA Oncol 2018, 4:e181771.
  • Plasma level of LDL-cholesterol at diagnosis is a predictor factor of breast tumor progression. dos Santos, C.R., et al. BMC cancer, 2014. Feb 26;14:132. doi: 10.1186/1471-2407-14-132.  
  • 27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology. Nelson, E.R., et al., Science, 2013. 342(6162): p. 1094-8.

This list was last updated on 26/09/2019